Smoothies are common blended, sometimes sweetened beverages and the main fair of Mr. Smoothy stores.
Throughout the course of Ben 10: Alien Force, Ben 10: Ultimate Alien and Ben 10: Omniverse They are shown to be one of Ben Tennyson's favorite beverages and as such he, Gwen and Kevin are often seen drinking them together. Ben has an addiction to it and has shown to be able to drink 2-3 of it without apparent difficulty. However, Ben reportedly disliked them when he was younger as shown in the Omniverse flashbacks. They are often made from fruits, though they are also known to be made from more unusual materials, such as meat. As shown in the episode Andreas' Fault, after Ben acquired fame the smoothies had special flavors that were based on different aliens of Ben. According to a fan, the Alien X one tastes like sandpaper. As shown in So Long, and Thanks for All the Smoothies, After Ben recreated the Universe, he failed to replicate the exact taste of the grape flavored smoothie.
- Driba and Blukic have also shown an interest for Smoothies, particularly the grasshopper flavored one.