Azmuth returns to Ultimate Alien in Map of Infinity, right after Ultimate Aggregor defeated Ben and his team. He tells Ben and his group about the Map of Infinity, an item Ultimate Aggregor is planning to steal in order to go to a location called the Forge of Creation. He also mocks the Ultimatrix, saying it is "pathetic workmanship." Azmuth reveals that he is constructing a third Omnitrix. He also refuses to let Ben have it, because he is too reckless and requires much patience. In addition, it wasn't completed anyway. He also thinks that adding an evolutionary feature to the Ultimatrix was a terrible idea, that is just "begging for trouble". He introduces Ben and the team to Galvan Mark II, Galvan Prime rebuilt. He later puts Max in a tube to replace his damaged nervous system, caused by Ultimate Aggregor.
In Perplexahedron, Azmuth was not happy with Ben's failures over losing three pieces of the Map of Infinity; he told Ben where the final piece was.
In The Forge of Creation, Azmuth was still not happy with Ben's failure and his loss of all four pieces of the map; he scolds Ben and his team about letting Ultimate Aggregor beat them each time when they had four opportunities to stop him. After Paradox transforms Alien X back to Ben, Azmuth has an argument with Paradox about Ben and his friend's ability to save the universe this time. Azmuth also says that trusting Ben with the Omnitrix was a "grave mistake" though Paradox had said that it was not a mistake at all, and that he and Azmuth knew the reasons why all too well. Azmuth resentfully begins to reveal that Paradox had told him that Ben was a legendary being born with incomprehensible, immeasurable power, and that he would someday do something amazing, as it was his "grand destiny," but Paradox interrupted him, saying that there must be "no spoilers."
In The Transmogrification of Eunice, Azmuth is little in Sunder and Ben's battle for the Unitrix and seeing Ben and Sunder fighting in a muddy area. He is also the one who hired Sunder to retrieve the Unitrix. He had told Ben and his team about the Omnitrix prototype called the Unitrix. He had an argument with Ben about Eunice's life but, after being impressed by Ben's strong defense over Eunice and his belief about his aliens, he agreed to a compromise and allowed her to live a free life as one of his assistants. He stated that he always needed help tending to Primus.In Simian Says, Eunice contacted Azmuth about the degradation of the Arachnichimp DNA sample on Primus; he angrily told her to send Voliticus Biopsis to get a fresh sample.
In The Ultimate Sacrifice, Azmuth saves Ben from death and frees the Ultimates from the Ultimatrix. Ben has regained Azmuth's trust, it seems, as he was willing to sacrifice himself for his aliens' freedom.
In Solitary Alignment, Azmuth becomes involved with the Forever Knights by claiming that the sword Sir George used to fight Diagon with is his, which leads Ben to question him about the first knight. Azmuth reluctantly agrees to tell his origins and one of his early inventions.
In The Ultimate Enemy: Part 2, Azmuth came to reclaim Ascalon and the Ultimatrix, and in return gave Ben the new Omnitrix after Ben proved himself worthy of having the Omnitrix. Azmuth didn't add the Ultimate Forms to the new Omnitrix, and nothing will replace them in Ben 10: Omniverse.